Dichloromethane-d

Dichloromethane-d is carcinogenic, is a skin and eye irritant, should not be ingested, and is a teratogen, however it is considered to be the least toxic of the chlorinated methanes. As such, it is marginally better than chloroform.
 * As an NMR solvent, it has similar polarity (and therefore, similar substances will be soluble in it) to chloroform, making it a good substitute.
 * The major drawback to substituting dichloromethane for chloroform is cost; a 5mL bottle of dichloromethane costs about ten times the amount of the same size bottle of chloroform.

MSDS information .